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P53/PANK1/miR‐107 signalling pathway spans the gap between metabolic reprogramming and insulin resistance induced by high‐fat diet

High‐fat diet (HFD) leads to obesity, type II diabetes mellitus (T2DM) and increases the coincidence of cardiovascular diseases and cancer. Insulin resistance (IR) is considered as the ‘common soil’ of those diseases. Furthermore, people on HFD showed restrained glycolysis and enhanced fatty acid ox...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Zhang, Bin, Wang, Xinju, Liu, Zhenhua, Li, Juan, Zhang, Shumiao, Gu, Xiaoming, Jia, Min, Guo, Haitao, Feng, Na, Fan, Rong, Xie, Manjiang, Pei, Jianming, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131928/
https://www.ncbi.nlm.nih.gov/pubmed/32048816
http://dx.doi.org/10.1111/jcmm.15053