Cargando…

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

Weight loss by ketogenic diet (KD) has gained popularity in management of nonalcoholic fatty liver disease (NAFLD). KD rapidly reverses NAFLD and insulin resistance despite increasing circulating nonesterified fatty acids (NEFA), the main substrate for synthesis of intrahepatic triglycerides (IHTG)....

Descripción completa

Detalles Bibliográficos
Autores principales:	Luukkonen, Panu K., Dufour, Sylvie, Lyu, Kun, Zhang, Xian-Man, Hakkarainen, Antti, Lehtimäki, Tiina E., Cline, Gary W., Petersen, Kitt Falk, Shulman, Gerald I., Yki-Järvinen, Hannele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132133/ https://www.ncbi.nlm.nih.gov/pubmed/32179679 http://dx.doi.org/10.1073/pnas.1922344117

Ejemplares similares

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly
por: Flannery, Clare, et al.
Publicado: (2012)

Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) – an 11-Year Prospective Study
por: Lallukka, Susanna, et al.
Publicado: (2017)

Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis
por: Luukkonen, Panu K., et al.
Publicado: (2023)

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
por: Jian, Ching, et al.
Publicado: (2020)

Ethnic and sex differences in hepatic lipid content and related cardiometabolic parameters in lean individuals
por: Petersen, Kitt Falk, et al.
Publicado: (2022)

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease
por: Soronen, Jarkko, et al.
Publicado: (2016)

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease
por: Luukkonen, Panu K., et al.
Publicado: (2022)

Continuous Grading of Early Fibrosis in NAFLD Using Label-Free Imaging: A Proof-of-Concept Study
por: Pirhonen, Juho, et al.
Publicado: (2016)

Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic (13)C magnetic resonance spectroscopy
por: Befroy, Douglas E., et al.
Publicado: (2013)

Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver
por: Kotronen, Anna, et al.
Publicado: (2009)

Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
por: ter Horst, Kasper W., et al.
Publicado: (2017)

Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD
por: Petäjä, Elina M., et al.
Publicado: (2016)

Apolipoprotein CIII Overexpressing Mice Are Predisposed to Diet-Induced Hepatic Steatosis and Hepatic Insulin Resistance
por: Lee, Hui-Young, et al.
Publicado: (2011)

Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis
por: Koo, Seung-Hoi
Publicado: (2013)

Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease
por: Qadri, Sami, et al.
Publicado: (2021)

A noninvasive diagnostic model to assess nonalcoholic hepatic steatosis in patients with chronic hepatitis B
por: Ou, Hongjie, et al.
Publicado: (2016)

Nonalcoholic Fatty Liver Disease: Noninvasive Methods of Diagnosing Hepatic Steatosis
por: AlShaalan, Rasha, et al.
Publicado: (2015)

Hepatic Steatosis in Infancy: The Beginning of Pediatric Nonalcoholic Fatty Liver Disease?
por: McNelis, Kera, et al.
Publicado: (2021)

Ketogenic Essential Amino Acids Modulate Lipid Synthetic Pathways and Prevent Hepatic Steatosis in Mice
por: Noguchi, Yasushi, et al.
Publicado: (2010)

Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents
por: Petersen, Kitt F, et al.
Publicado: (2005)

Overfeeding Saturated Fat Increases LDL (Low-Density Lipoprotein) Aggregation Susceptibility While Overfeeding Unsaturated Fat Decreases Proteoglycan-Binding of Lipoproteins
por: Ruuth, Maija, et al.
Publicado: (2021)

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism
por: Perry, Rachel J., et al.
Publicado: (2016)

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance
por: Yki-Järvinen, Hannele
Publicado: (2015)

Role of Patatin-Like Phospholipase Domain-Containing 3 on Lipid-Induced Hepatic Steatosis and Insulin Resistance in Rats
por: Kumashiro, Naoki, et al.
Publicado: (2013)

Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)
por: Perry, Rachel J., et al.
Publicado: (2017)

Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis
por: Lee, Hyo Young, et al.
Publicado: (2019)

Magnesium isoglycyrrhizinate prevents the nonalcoholic hepatic steatosis via regulating energy homeostasis
por: Jiang, Wenjiao, et al.
Publicado: (2020)

Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis
por: Li, Jinwang, et al.
Publicado: (2021)

Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice
por: Abulizi, Abudukadier, et al.
Publicado: (2020)

Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)
por: Perry, Rachel J., et al.
Publicado: (2018)

The effects of increased acetate turnover on glucose-induced insulin secretion in lean and obese humans
por: Petersen, Kitt Falk, et al.
Publicado: (2019)

Lipopolysaccharides accelerate hepatic steatosis in the development of nonalcoholic fatty liver disease in Zucker rats
por: Fukunishi, Shinya, et al.
Publicado: (2014)

Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease
por: Pirmoazen, Amir M., et al.
Publicado: (2020)

Change in skeletal muscle mass is associated with hepatic steatosis in nonalcoholic fatty liver disease
por: Jo, Ik Hyun, et al.
Publicado: (2023)

Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
por: Mu, Chunlong, et al.
Publicado: (2022)

Quinoa Ameliorates Hepatic Steatosis, Oxidative Stress, Inflammation and Regulates the Gut Microbiota in Nonalcoholic Fatty Liver Disease Rats
por: Zhong, Lingyue, et al.
Publicado: (2023)

Prevention of Nonalcoholic Hepatic Steatosis by Shenling Baizhu Powder: Involvement of Adiponectin-Induced Inhibition of Hepatic SREBP-1c
por: Tang, Kairui, et al.
Publicado: (2020)

Risk of advanced fibrosis in first-degree relatives of patients with nonalcoholic fatty liver disease
por: Tamaki, Nobuharu, et al.
Publicado: (2022)

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
por: Luukkonen, Panu K., et al.
Publicado: (2018)

Is There Evidence to Support Use of Premixed or Prandial Insulin Regimens in Insulin-Naive or Previously Insulin-Treated Type 2 Diabetic Patients?
por: Yki-Järvinen, Hannele, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3n25rd7ru1cafoio0dpf9mst9j