Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis

Two isoforms of the 70-kDa ribosomal protein S6 kinase, S6K1 and S6K2, have been identified and are considered key downstream effectors of the mTOR signaling pathway, which is involved in tumor growth and progression. However, their biological roles in the tumor microenvironment are poorly understoo...

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Detalles Bibliográficos
Autores principales: Lee, Seul, Roh, Hyun-Soo, Song, Seong-Soo, Shin, Jimin, Lee, Jangchoon, Bhang, Dong Ha, Kim, Byung Gak, Um, Sung Hee, Jeong, Han-Sin, Baek, Kwan-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132264/
https://www.ncbi.nlm.nih.gov/pubmed/32251993
http://dx.doi.org/10.1016/j.tranon.2020.100767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132264/
https://www.ncbi.nlm.nih.gov/pubmed/32251993
http://dx.doi.org/10.1016/j.tranon.2020.100767

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