NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

Neutrophil extracellular traps (NETs) are web-like DNA structures decorated with histones and cytotoxic proteins that are released by activated neutrophils to trap and neutralize pathogens during the innate immune response, but also form in and exacerbate sterile inflammation. Peptidylarginine deimi...

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Detalles Bibliográficos
Autores principales: Thiam, Hawa Racine, Wong, Siu Ling, Qiu, Rong, Kittisopikul, Mark, Vahabikashi, Amir, Goldman, Anne E., Goldman, Robert D., Wagner, Denisa D., Waterman, Clare M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132277/
https://www.ncbi.nlm.nih.gov/pubmed/32170015
http://dx.doi.org/10.1073/pnas.1909546117

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