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Human RAP1 specifically protects telomeres of senescent cells from DNA damage
Repressor/activator protein 1 (RAP1) is a highly evolutionarily conserved protein found at telomeres. Although yeast Rap1 is a key telomere capping protein preventing non‐homologous end joining (NHEJ) and consequently telomere fusions, its role at mammalian telomeres in vivo is still controversial....
Autores principales: | Lototska, Liudmyla, Yue, Jia‐Xing, Li, Jing, Giraud‐Panis, Marie‐Josèphe, Songyang, Zhou, Royle, Nicola J, Liti, Gianni, Ye, Jing, Gilson, Eric, Mendez‐Bermudez, Aaron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132343/ https://www.ncbi.nlm.nih.gov/pubmed/32096305 http://dx.doi.org/10.15252/embr.201949076 |
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