Cargando…

MEX3A regulates Lgr5 (+) stem cell maintenance in the developing intestinal epithelium

Intestinal stem cells (ISCs) fuel the lifelong self‐renewal of the intestinal tract and are paramount for epithelial repair. In this context, the Wnt pathway component LGR5 is the most consensual ISC marker to date. Still, the effort to better understand ISC identity and regulation remains a challen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pereira, Bruno, Amaral, Ana L, Dias, Alexandre, Mendes, Nuno, Muncan, Vanesa, Silva, Ana R, Thibert, Chantal, Radu, Anca G, David, Leonor, Máximo, Valdemar, van den Brink, Gijs R, Billaud, Marc, Almeida, Raquel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132344/ https://www.ncbi.nlm.nih.gov/pubmed/32052574 http://dx.doi.org/10.15252/embr.201948938

Ejemplares similares

LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea
por: Żak, Magdalena, et al.
Publicado: (2016)

AMPK potentiation by LKB1 isoforms
por: Thibert, Chantal, et al.
Publicado: (2015)

Rage mediated DAMP signaling in intestinal tumorigenesis
por: Heijmans, Jarom, et al.
Publicado: (2012)

Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium
por: Leushacke, Marc, et al.
Publicado: (2016)

Monolayer culture of intestinal epithelium sustains Lgr5(+) intestinal stem cells
por: Liu, Yuan, et al.
Publicado: (2018)

Lgr5(+) cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages
por: Ren, Wenwen, et al.
Publicado: (2022)

Blimp1 regulates the transition of neonatal to adult intestinal epithelium
por: Muncan, Vanesa, et al.
Publicado: (2011)

Core clock gene BMAL1 and RNA-binding protein MEX3A collaboratively regulate Lgr5 expression in intestinal crypt cells
por: Cheng, Li-Tzu, et al.
Publicado: (2023)

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation
por: Tsai, Yu-Hwai, et al.
Publicado: (2016)

Marcas & trademarks mex /
por: Larrea Cruces, Quim
Publicado: (2009)

LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells
por: CHEN, XIANG, et al.
Publicado: (2014)

Generating tissue-engineered intestinal epithelium from cultured Lgr5 stem cells in vivo
por: Baimakhanov, Zhassulan, et al.
Publicado: (2016)

siRNA-mediated gene silencing of MexB from the MexA-MexB-OprM efflux pump in Pseudomonas aeruginosa
por: Gong, Feng-Yun, et al.
Publicado: (2014)

The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradation
por: Cano, Florencia, et al.
Publicado: (2012)

Molecular Determinants of the Promiscuity of MexB and MexY Multidrug Transporters of Pseudomonas aeruginosa
por: Ramaswamy, Venkata K., et al.
Publicado: (2018)

LGR5 and LGR6 in stem cell biology and ovarian cancer
por: Schindler, Adam J., et al.
Publicado: (2017)

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness
por: Pereira, Bruno, et al.
Publicado: (2013)

Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence
por: Vaillancourt, Mylene, et al.
Publicado: (2021)

Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
por: Lee, Joo-Hyeon, et al.
Publicado: (2017)

Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface
por: López, Cesar A., et al.
Publicado: (2017)

Interplay between MexAB-OprM and MexEF-OprN in clinical isolates of Pseudomonas aeruginosa
por: Horna, Gertrudis, et al.
Publicado: (2018)

Involvement of MexS and MexEF-OprN in Resistance to Toxic Ion Chelators in Pseudomonas putida KT2440
por: Henriquez, Tania, et al.
Publicado: (2020)

Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA
por: Cacciotto, Pierpaolo, et al.
Publicado: (2021)

Expression of UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell proliferation and stemness by activating PERK signaling
por: Spaan, Claudia N., et al.
Publicado: (2019)

Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway
por: Li, Xuewen, et al.
Publicado: (2020)

Antibacterial Effect of 16 Essential Oils and Modulation of mex Efflux Pumps Gene Expression on Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates: Is Cinnamon a Good Fighter?
por: Coșeriu, Răzvan Lucian, et al.
Publicado: (2023)

Construcción de bodega tipo tel-mex
por: Rivera Aguilar, Hugo
Publicado: (1992)

Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea
por: Cheng, Cheng, et al.
Publicado: (2017)

Evidence of MexT-Independent Overexpression of MexEF-OprN Multidrug Efflux Pump of Pseudomonas aeruginosa in Presence of Metabolic Stress
por: Kumar, Ayush, et al.
Publicado: (2011)

Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ
por: Hay, Thomas, et al.
Publicado: (2013)

Crystal Structure of the Regulatory Domain of MexT, a Transcriptional Activator of the MexEF-OprN Efflux Pump in Pseudomonas aeruginosa
por: Kim, Suhyeon, et al.
Publicado: (2019)

LGR6 marks nephron progenitor cells
por: van Ineveld, Ravian L., et al.
Publicado: (2021)

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies
por: Buchet-Poyau, Karine, et al.
Publicado: (2007)

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands
por: Toh, Yukimatsu, et al.
Publicado: (2023)

Lgr4 in Ocular Development and Glaucoma
por: Siwko, Stefan, et al.
Publicado: (2013)

Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex
por: Glavier, Marie, et al.
Publicado: (2020)

Colorectal tumor prevention by the progestin medroxyprogesterone acetate is critically dependent on postmenopausal status
por: Meijer, Bartolomeus J., et al.
Publicado: (2018)

Mouse fetal intestinal organoids: new model to study epithelial maturation from suckling to weaning
por: Navis, Marit, et al.
Publicado: (2018)

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5
por: Ruffner, Heinz, et al.
Publicado: (2012)

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy
por: Xu, Liangliang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_o62t6ha76ubm3ja0q09m6c86iq