Clinical manifestations of mannan-binding lectin deficiency

Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy...

Descripción completa

Detalles Bibliográficos
Autores principales: Thiel, S., Frederiksen, P.D., Jensenius, J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132399/
https://www.ncbi.nlm.nih.gov/pubmed/16023210
http://dx.doi.org/10.1016/j.molimm.2005.06.018
_version_ 1783517428777484288
author Thiel, S.
Frederiksen, P.D.
Jensenius, J.C.
author_facet Thiel, S.
Frederiksen, P.D.
Jensenius, J.C.
author_sort Thiel, S.
collection PubMed
description Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far.
format Online
Article
Text
id pubmed-7132399
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-71323992020-04-08 Clinical manifestations of mannan-binding lectin deficiency Thiel, S. Frederiksen, P.D. Jensenius, J.C. Mol Immunol Article Mannan-binding lectin (MBL) is a plasma protein of the innate immune system with the ability to initiate antimicrobial and inflammatory actions. MBL deficiency is common. More than 10% of the general population may, depending on definition, be classified as MBL deficient, underlining the redundancy of the immune system. Ongoing research attempt to illuminate at which conditions MBL deficiency may lead to disease. With examples, this review illustrates the diversity of results obtained so far. Elsevier Ltd. 2006-01 2005-07-14 /pmc/articles/PMC7132399/ /pubmed/16023210 http://dx.doi.org/10.1016/j.molimm.2005.06.018 Text en Copyright © 2005 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Thiel, S.
Frederiksen, P.D.
Jensenius, J.C.
Clinical manifestations of mannan-binding lectin deficiency
title Clinical manifestations of mannan-binding lectin deficiency
title_full Clinical manifestations of mannan-binding lectin deficiency
title_fullStr Clinical manifestations of mannan-binding lectin deficiency
title_full_unstemmed Clinical manifestations of mannan-binding lectin deficiency
title_short Clinical manifestations of mannan-binding lectin deficiency
title_sort clinical manifestations of mannan-binding lectin deficiency
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132399/
https://www.ncbi.nlm.nih.gov/pubmed/16023210
http://dx.doi.org/10.1016/j.molimm.2005.06.018
work_keys_str_mv AT thiels clinicalmanifestationsofmannanbindinglectindeficiency
AT frederiksenpd clinicalmanifestationsofmannanbindinglectindeficiency
AT jenseniusjc clinicalmanifestationsofmannanbindinglectindeficiency

Ejemplares similares