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An investigation into the design of a device to treat haemorrhagic stroke

In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle ce...

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Autores principales: Randhawa, Hardeep Singh, Pearce, Gillian, Hepton, Rachel, Wong, Julian, Zidane, Iham F, Ma, Xianghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132436/
https://www.ncbi.nlm.nih.gov/pubmed/31774350
http://dx.doi.org/10.1177/0954411919890698
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author Randhawa, Hardeep Singh
Pearce, Gillian
Hepton, Rachel
Wong, Julian
Zidane, Iham F
Ma, Xianghong
author_facet Randhawa, Hardeep Singh
Pearce, Gillian
Hepton, Rachel
Wong, Julian
Zidane, Iham F
Ma, Xianghong
author_sort Randhawa, Hardeep Singh
collection PubMed
description In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle cerebral artery in the brain. We evaluate and model these three designs using computer aided design software, SolidWorks, which allows the devices to be tested using finite element analysis and also enables us to justify that the materials chosen were suitable for potential use. Computational fluid dynamics modelling were used to demonstrate and analyse the flow of blood through the artery under conditions of normal and ruptured states. We conclude that our device could potentially be useful in the treatment of hemorrhagic stroke, and the modelling process is useful in assisting in determining the performance of our devices.
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spelling pubmed-71324362020-04-17 An investigation into the design of a device to treat haemorrhagic stroke Randhawa, Hardeep Singh Pearce, Gillian Hepton, Rachel Wong, Julian Zidane, Iham F Ma, Xianghong Proc Inst Mech Eng H Original Articles In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle cerebral artery in the brain. We evaluate and model these three designs using computer aided design software, SolidWorks, which allows the devices to be tested using finite element analysis and also enables us to justify that the materials chosen were suitable for potential use. Computational fluid dynamics modelling were used to demonstrate and analyse the flow of blood through the artery under conditions of normal and ruptured states. We conclude that our device could potentially be useful in the treatment of hemorrhagic stroke, and the modelling process is useful in assisting in determining the performance of our devices. SAGE Publications 2019-11-27 2020-04 /pmc/articles/PMC7132436/ /pubmed/31774350 http://dx.doi.org/10.1177/0954411919890698 Text en © IMechE 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Randhawa, Hardeep Singh
Pearce, Gillian
Hepton, Rachel
Wong, Julian
Zidane, Iham F
Ma, Xianghong
An investigation into the design of a device to treat haemorrhagic stroke
title An investigation into the design of a device to treat haemorrhagic stroke
title_full An investigation into the design of a device to treat haemorrhagic stroke
title_fullStr An investigation into the design of a device to treat haemorrhagic stroke
title_full_unstemmed An investigation into the design of a device to treat haemorrhagic stroke
title_short An investigation into the design of a device to treat haemorrhagic stroke
title_sort investigation into the design of a device to treat haemorrhagic stroke
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132436/
https://www.ncbi.nlm.nih.gov/pubmed/31774350
http://dx.doi.org/10.1177/0954411919890698
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