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An investigation into the design of a device to treat haemorrhagic stroke
In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle ce...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132436/ https://www.ncbi.nlm.nih.gov/pubmed/31774350 http://dx.doi.org/10.1177/0954411919890698 |
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author | Randhawa, Hardeep Singh Pearce, Gillian Hepton, Rachel Wong, Julian Zidane, Iham F Ma, Xianghong |
author_facet | Randhawa, Hardeep Singh Pearce, Gillian Hepton, Rachel Wong, Julian Zidane, Iham F Ma, Xianghong |
author_sort | Randhawa, Hardeep Singh |
collection | PubMed |
description | In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle cerebral artery in the brain. We evaluate and model these three designs using computer aided design software, SolidWorks, which allows the devices to be tested using finite element analysis and also enables us to justify that the materials chosen were suitable for potential use. Computational fluid dynamics modelling were used to demonstrate and analyse the flow of blood through the artery under conditions of normal and ruptured states. We conclude that our device could potentially be useful in the treatment of hemorrhagic stroke, and the modelling process is useful in assisting in determining the performance of our devices. |
format | Online Article Text |
id | pubmed-7132436 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71324362020-04-17 An investigation into the design of a device to treat haemorrhagic stroke Randhawa, Hardeep Singh Pearce, Gillian Hepton, Rachel Wong, Julian Zidane, Iham F Ma, Xianghong Proc Inst Mech Eng H Original Articles In this study, we present the design considerations of a device to assist in the potential treatment of hemorrhagic stroke with the aim of stopping blood from flowing out into brain tissue. We present and model three designs for the clinical scenarios when saccular aneurysms rupture in the middle cerebral artery in the brain. We evaluate and model these three designs using computer aided design software, SolidWorks, which allows the devices to be tested using finite element analysis and also enables us to justify that the materials chosen were suitable for potential use. Computational fluid dynamics modelling were used to demonstrate and analyse the flow of blood through the artery under conditions of normal and ruptured states. We conclude that our device could potentially be useful in the treatment of hemorrhagic stroke, and the modelling process is useful in assisting in determining the performance of our devices. SAGE Publications 2019-11-27 2020-04 /pmc/articles/PMC7132436/ /pubmed/31774350 http://dx.doi.org/10.1177/0954411919890698 Text en © IMechE 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Randhawa, Hardeep Singh Pearce, Gillian Hepton, Rachel Wong, Julian Zidane, Iham F Ma, Xianghong An investigation into the design of a device to treat haemorrhagic stroke |
title | An investigation into the design of a device to treat haemorrhagic
stroke |
title_full | An investigation into the design of a device to treat haemorrhagic
stroke |
title_fullStr | An investigation into the design of a device to treat haemorrhagic
stroke |
title_full_unstemmed | An investigation into the design of a device to treat haemorrhagic
stroke |
title_short | An investigation into the design of a device to treat haemorrhagic
stroke |
title_sort | investigation into the design of a device to treat haemorrhagic
stroke |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132436/ https://www.ncbi.nlm.nih.gov/pubmed/31774350 http://dx.doi.org/10.1177/0954411919890698 |
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