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Airborne transmission and precautions: facts and myths
Airborne transmission occurs only when infectious particles of <5 μm, known as aerosols, are propelled into the air. The prevention of such transmission is expensive, requiring N95 respirators and negative pressure isolation rooms. This lecture first discussed whether respiratory viral infections...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Published by Elsevier Ltd.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132528/ https://www.ncbi.nlm.nih.gov/pubmed/25578684 http://dx.doi.org/10.1016/j.jhin.2014.11.005 |
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author | Seto, W.H. |
author_facet | Seto, W.H. |
author_sort | Seto, W.H. |
collection | PubMed |
description | Airborne transmission occurs only when infectious particles of <5 μm, known as aerosols, are propelled into the air. The prevention of such transmission is expensive, requiring N95 respirators and negative pressure isolation rooms. This lecture first discussed whether respiratory viral infections are airborne with reference to published reviews of studies before 2008, comparative trials of surgical masks and N95 respirators, and relevant new experimental studies. However, the most recent experimental study, using naturally infected influenza volunteers as the source, showed negative results from all the manikins that were exposed. Modelling studies by ventilation engineers were then summarized to explain why these results were not unexpected. Second, the systematic review commissioned by the World Health Organization on what constituted aerosol-generating procedures was summarized. From the available evidence, endotracheal intubation either by itself or combined with other procedures (e.g. cardiopulmonary resuscitation or bronchoscopy) was consistently associated with increased risk of transmission by the generation of aerosols. |
format | Online Article Text |
id | pubmed-7132528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71325282020-04-08 Airborne transmission and precautions: facts and myths Seto, W.H. J Hosp Infect Article Airborne transmission occurs only when infectious particles of <5 μm, known as aerosols, are propelled into the air. The prevention of such transmission is expensive, requiring N95 respirators and negative pressure isolation rooms. This lecture first discussed whether respiratory viral infections are airborne with reference to published reviews of studies before 2008, comparative trials of surgical masks and N95 respirators, and relevant new experimental studies. However, the most recent experimental study, using naturally infected influenza volunteers as the source, showed negative results from all the manikins that were exposed. Modelling studies by ventilation engineers were then summarized to explain why these results were not unexpected. Second, the systematic review commissioned by the World Health Organization on what constituted aerosol-generating procedures was summarized. From the available evidence, endotracheal intubation either by itself or combined with other procedures (e.g. cardiopulmonary resuscitation or bronchoscopy) was consistently associated with increased risk of transmission by the generation of aerosols. Published by Elsevier Ltd. 2015-04 2014-12-13 /pmc/articles/PMC7132528/ /pubmed/25578684 http://dx.doi.org/10.1016/j.jhin.2014.11.005 Text en Copyright © 2014 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Seto, W.H. Airborne transmission and precautions: facts and myths |
title | Airborne transmission and precautions: facts and myths |
title_full | Airborne transmission and precautions: facts and myths |
title_fullStr | Airborne transmission and precautions: facts and myths |
title_full_unstemmed | Airborne transmission and precautions: facts and myths |
title_short | Airborne transmission and precautions: facts and myths |
title_sort | airborne transmission and precautions: facts and myths |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132528/ https://www.ncbi.nlm.nih.gov/pubmed/25578684 http://dx.doi.org/10.1016/j.jhin.2014.11.005 |
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