HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome

Components of bacteria and viruses activate Toll-Like Receptors in host cells, triggering the formation of the Myddosome and a signalling network that culminates in the production and release of the inflammatory mediators required to combat pathogenic infection. The Myddosome initiates signalling by...

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Detalles Bibliográficos
Autores principales: Cohen, Philip, Kelsall, Ian R., Nanda, Sambit K., Zhang, Jiazhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132539/
https://www.ncbi.nlm.nih.gov/pubmed/31615747
http://dx.doi.org/10.1016/j.jbior.2019.100666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132539/
https://www.ncbi.nlm.nih.gov/pubmed/31615747
http://dx.doi.org/10.1016/j.jbior.2019.100666

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