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Effect simultaneous delivery with P-glycoprotein inhibitor and nanoparticle administration of doxorubicin on cellular uptake and in vitro anticancer activity

Multidrug resistance (MDR) is the most common problem of inadequate therapeutic response in tumor cells. Many trials has been developed to overcome drug efflux by P-glycoprotein (P-gp). For instance, co-administration of a number of drugs called chemosensitizers or MDR modulators with a chemotherape...

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Detalles Bibliográficos
Autores principales: Esim, Ozgur, Sarper, Meral, Ozkan, Cansel K., Oren, Sema, Baykal, Baris, Savaser, Ayhan, Ozkan, Yalcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132609/
https://www.ncbi.nlm.nih.gov/pubmed/32273806
http://dx.doi.org/10.1016/j.jsps.2020.02.008