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Acute Disseminated Encephalomyelitis: Clinical and Pathogenesis Features

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADE...

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Detalles Bibliográficos
Autores principales: Noorbakhsh, Farshid, Johnson, Richard T., Emery, Derek, Power, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132764/
https://www.ncbi.nlm.nih.gov/pubmed/18657725
http://dx.doi.org/10.1016/j.ncl.2008.03.009
Descripción
Sumario:Acute disseminated encephalomyelitis (ADEM) is an immune-mediated disorder of the central nervous system (CNS). Disease typically starts with an abrupt onset of neurologic symptoms and signs within days to weeks after a viral infection or immunization. Neuropathological examination of the CNS in ADEM reveals involvement of white matter, with infiltration of monocytoid cells and perivenous demyelination.