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Gallbladder wall abnormality in biliary atresia of mouse Sox17(+/−) neonates and human infants

Biliary atresia (BA) is characterized by the inflammation and obstruction of the extrahepatic bile ducts (EHBDs) in newborn infants. SOX17 is a master regulator of fetal EHBD formation. In mouse Sox17(+/−) BA models, SOX17 reduction causes cell-autonomous epithelial shedding together with the ectopi...

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Detalles Bibliográficos
Autores principales: Uemura, Mami, Higashi, Mayumi, Pattarapanawan, Montri, Takami, Shohei, Ichikawa, Naoki, Higashiyama, Hiroki, Furukawa, Taizo, Fujishiro, Jun, Fukumura, Yuki, Yao, Takashi, Tajiri, Tatsuro, Kanai-Azuma, Masami, Kanai, Yoshiakira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132780/
https://www.ncbi.nlm.nih.gov/pubmed/31996362
http://dx.doi.org/10.1242/dmm.042119