Cargando…
Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome
OBJECTIVE: This study was performed to evaluate the endocrine and glycolipid metabolism characteristics of diminished ovarian reserve (DOR) in Chinese patients with polycystic ovary syndrome (PCOS). METHODS: In total, 1179 patients with PCOS and 70 healthy women who presented to the Department of Gy...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132792/ https://www.ncbi.nlm.nih.gov/pubmed/32228335 http://dx.doi.org/10.1177/0300060520912982 |
_version_ | 1783517506681438208 |
---|---|
author | Wang, Chaojun Di, Wen Gu, Zhuowei |
author_facet | Wang, Chaojun Di, Wen Gu, Zhuowei |
author_sort | Wang, Chaojun |
collection | PubMed |
description | OBJECTIVE: This study was performed to evaluate the endocrine and glycolipid metabolism characteristics of diminished ovarian reserve (DOR) in Chinese patients with polycystic ovary syndrome (PCOS). METHODS: In total, 1179 patients with PCOS and 70 healthy women who presented to the Department of Gynecological Endocrinology in Ren Ji Hospital from June 2015 and June 2019 were enrolled in this study. Parameters of endocrine and glycolipid metabolism were measured. The differences in indices among the control group, simple PCOS group, and PCOS with DOR group were analyzed. RESULTS: The prevalence of DOR in Chinese women with PCOS was 20.8%. The body mass index and waist/hip ratio were significantly higher in the simple PCOS group than in the PCOS with DOR group. There were significant differences in the concentrations of luteinizing hormone, follicle-stimulating hormone, estradiol, testosterone, and androstenedione among the three groups. The fasting serum insulin concentration and homeostatic model assessment of insulin resistance were significantly higher in the simple PCOS group than in the PCOS with DOR group. CONCLUSIONS: The endocrine and glycolipid metabolism characteristics were different between the simple PCOS group and PCOS with DOR group. |
format | Online Article Text |
id | pubmed-7132792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71327922020-04-13 Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome Wang, Chaojun Di, Wen Gu, Zhuowei J Int Med Res Retrospective Clinical Research Report OBJECTIVE: This study was performed to evaluate the endocrine and glycolipid metabolism characteristics of diminished ovarian reserve (DOR) in Chinese patients with polycystic ovary syndrome (PCOS). METHODS: In total, 1179 patients with PCOS and 70 healthy women who presented to the Department of Gynecological Endocrinology in Ren Ji Hospital from June 2015 and June 2019 were enrolled in this study. Parameters of endocrine and glycolipid metabolism were measured. The differences in indices among the control group, simple PCOS group, and PCOS with DOR group were analyzed. RESULTS: The prevalence of DOR in Chinese women with PCOS was 20.8%. The body mass index and waist/hip ratio were significantly higher in the simple PCOS group than in the PCOS with DOR group. There were significant differences in the concentrations of luteinizing hormone, follicle-stimulating hormone, estradiol, testosterone, and androstenedione among the three groups. The fasting serum insulin concentration and homeostatic model assessment of insulin resistance were significantly higher in the simple PCOS group than in the PCOS with DOR group. CONCLUSIONS: The endocrine and glycolipid metabolism characteristics were different between the simple PCOS group and PCOS with DOR group. SAGE Publications 2020-03-31 /pmc/articles/PMC7132792/ /pubmed/32228335 http://dx.doi.org/10.1177/0300060520912982 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Wang, Chaojun Di, Wen Gu, Zhuowei Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title | Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title_full | Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title_fullStr | Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title_full_unstemmed | Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title_short | Endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in Chinese women with polycystic ovary syndrome |
title_sort | endocrine and glycolipid metabolism characteristics of diminished ovarian reserve in chinese women with polycystic ovary syndrome |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132792/ https://www.ncbi.nlm.nih.gov/pubmed/32228335 http://dx.doi.org/10.1177/0300060520912982 |
work_keys_str_mv | AT wangchaojun endocrineandglycolipidmetabolismcharacteristicsofdiminishedovarianreserveinchinesewomenwithpolycysticovarysyndrome AT diwen endocrineandglycolipidmetabolismcharacteristicsofdiminishedovarianreserveinchinesewomenwithpolycysticovarysyndrome AT guzhuowei endocrineandglycolipidmetabolismcharacteristicsofdiminishedovarianreserveinchinesewomenwithpolycysticovarysyndrome |