Long noncoding RNA TUG1 is downregulated in sepsis and may sponge miR-27a to downregulate tumor necrosis factor-α

OBJECTIVES: Bioinformatics analysis revealed a potential interaction between long noncoding (lnc)RNA TUG1 (taurine-upregulated gene 1) and microRNA (miR)-27a. miR-27a can promote sepsis by upregulating tumor necrosis factor-α (TNF-α). Our objective was to study the roles of TUG1 in sepsis. METHODS:...

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Detalles Bibliográficos
Autores principales: Wang, Li, Zhong, Qinghua, Feng, Yanli, Tang, Xiaoying, Wang, Qiong, Zou, Yongyi, Duan, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Prospective Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132817/
https://www.ncbi.nlm.nih.gov/pubmed/32237949
http://dx.doi.org/10.1177/0300060520910638

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