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Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy

Acquired pure red cell aplasia (PRCA) following use of recombinant erythropoietin (rEPO) is distinctly rare and sporadically reported in the literature. We discuss a case of PRCA following the usage of rEPO (darbepoetin-α) during the management of anemia of chronic kidney disease in an elderly male...

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Autores principales: Padhi, Somanath, Behera, Gayatri, Pattnaik, Sandeep Abhijit, Das, Prabodh Kumar, Adhya, Amit Kumar, Patra, Susama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132853/
https://www.ncbi.nlm.nih.gov/pubmed/32269436
http://dx.doi.org/10.4103/ijn.IJN_129_19
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author Padhi, Somanath
Behera, Gayatri
Pattnaik, Sandeep Abhijit
Das, Prabodh Kumar
Adhya, Amit Kumar
Patra, Susama
author_facet Padhi, Somanath
Behera, Gayatri
Pattnaik, Sandeep Abhijit
Das, Prabodh Kumar
Adhya, Amit Kumar
Patra, Susama
author_sort Padhi, Somanath
collection PubMed
description Acquired pure red cell aplasia (PRCA) following use of recombinant erythropoietin (rEPO) is distinctly rare and sporadically reported in the literature. We discuss a case of PRCA following the usage of rEPO (darbepoetin-α) during the management of anemia of chronic kidney disease in an elderly male subject with review of literature and a brief insight into proposed pathophysiologic mechanism, diagnosis, and management.
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spelling pubmed-71328532020-04-08 Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy Padhi, Somanath Behera, Gayatri Pattnaik, Sandeep Abhijit Das, Prabodh Kumar Adhya, Amit Kumar Patra, Susama Indian J Nephrol Case Report Acquired pure red cell aplasia (PRCA) following use of recombinant erythropoietin (rEPO) is distinctly rare and sporadically reported in the literature. We discuss a case of PRCA following the usage of rEPO (darbepoetin-α) during the management of anemia of chronic kidney disease in an elderly male subject with review of literature and a brief insight into proposed pathophysiologic mechanism, diagnosis, and management. Wolters Kluwer - Medknow 2020 2019-09-06 /pmc/articles/PMC7132853/ /pubmed/32269436 http://dx.doi.org/10.4103/ijn.IJN_129_19 Text en Copyright: © 2020 Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Padhi, Somanath
Behera, Gayatri
Pattnaik, Sandeep Abhijit
Das, Prabodh Kumar
Adhya, Amit Kumar
Patra, Susama
Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title_full Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title_fullStr Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title_full_unstemmed Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title_short Acquired Pure Red Cell Aplasia Following Recombinant Erythropoietin (Darbepoetin-alfa) Therapy
title_sort acquired pure red cell aplasia following recombinant erythropoietin (darbepoetin-alfa) therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132853/
https://www.ncbi.nlm.nih.gov/pubmed/32269436
http://dx.doi.org/10.4103/ijn.IJN_129_19
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