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MSX2 suppression through inhibition of TGFβ signaling enhances hematopoietic differentiation of human embryonic stem cells

BACKGROUND: Strategies of generating functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful due to the lack of a comprehensive understanding of hematopoietic development. Endothelial-to-hematopoietic transition (EHT) serves as the pivotal mechanism for the onset...

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Detalles Bibliográficos
Autores principales:	Wang, Hongtao, Wang, Mengge, Wang, Yu, Wen, Yuqi, Chen, Xiaoyuan, Wu, Dan, Su, Pei, Zhou, Wen, Shi, Lihong, Zhou, Jiaxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132876/ https://www.ncbi.nlm.nih.gov/pubmed/32248833 http://dx.doi.org/10.1186/s13287-020-01653-3

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