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DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes

BACKGROUND: Many CpGs become hyper or hypo-methylated with age. Multiple methods have been developed by Horvath et al. to estimate DNA methylation (DNAm) age including Pan-tissue, Skin & Blood, PhenoAge, and GrimAge. Pan-tissue and Skin & Blood try to estimate chronological age in the normal...

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Detalles Bibliográficos
Autores principales: Roshandel, Delnaz, Chen, Zhuo, Canty, Angelo J., Bull, Shelley B., Natarajan, Rama, Paterson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132894/
https://www.ncbi.nlm.nih.gov/pubmed/32248841
http://dx.doi.org/10.1186/s13148-020-00840-6