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Neural Dynamics of Associative Learning during Human Sleep
Recent evidence indicates that humans can learn entirely new information during sleep. To elucidate the neural dynamics underlying sleep-learning, we investigated brain activity during auditory–olfactory discriminatory associative learning in human sleep. We found that learning-related delta and sig...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132910/ https://www.ncbi.nlm.nih.gov/pubmed/31690927 http://dx.doi.org/10.1093/cercor/bhz197 |
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author | Canales-Johnson, Andrés Merlo, Emiliano Bekinschtein, Tristan A Arzi, Anat |
author_facet | Canales-Johnson, Andrés Merlo, Emiliano Bekinschtein, Tristan A Arzi, Anat |
author_sort | Canales-Johnson, Andrés |
collection | PubMed |
description | Recent evidence indicates that humans can learn entirely new information during sleep. To elucidate the neural dynamics underlying sleep-learning, we investigated brain activity during auditory–olfactory discriminatory associative learning in human sleep. We found that learning-related delta and sigma neural changes are involved in early acquisition stages, when new associations are being formed. In contrast, learning-related theta activity emerged in later stages of the learning process, after tone–odor associations were already established. These findings suggest that learning new associations during sleep is signaled by a dynamic interplay between slow-waves, sigma, and theta activity. |
format | Online Article Text |
id | pubmed-7132910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-71329102020-04-09 Neural Dynamics of Associative Learning during Human Sleep Canales-Johnson, Andrés Merlo, Emiliano Bekinschtein, Tristan A Arzi, Anat Cereb Cortex Original Article Recent evidence indicates that humans can learn entirely new information during sleep. To elucidate the neural dynamics underlying sleep-learning, we investigated brain activity during auditory–olfactory discriminatory associative learning in human sleep. We found that learning-related delta and sigma neural changes are involved in early acquisition stages, when new associations are being formed. In contrast, learning-related theta activity emerged in later stages of the learning process, after tone–odor associations were already established. These findings suggest that learning new associations during sleep is signaled by a dynamic interplay between slow-waves, sigma, and theta activity. Oxford University Press 2020-03 2019-11-05 /pmc/articles/PMC7132910/ /pubmed/31690927 http://dx.doi.org/10.1093/cercor/bhz197 Text en © The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Canales-Johnson, Andrés Merlo, Emiliano Bekinschtein, Tristan A Arzi, Anat Neural Dynamics of Associative Learning during Human Sleep |
title | Neural Dynamics of Associative Learning during Human Sleep |
title_full | Neural Dynamics of Associative Learning during Human Sleep |
title_fullStr | Neural Dynamics of Associative Learning during Human Sleep |
title_full_unstemmed | Neural Dynamics of Associative Learning during Human Sleep |
title_short | Neural Dynamics of Associative Learning during Human Sleep |
title_sort | neural dynamics of associative learning during human sleep |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132910/ https://www.ncbi.nlm.nih.gov/pubmed/31690927 http://dx.doi.org/10.1093/cercor/bhz197 |
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