Preserved Calretinin Interneurons in an App Model of Alzheimer’s Disease Disrupt Hippocampal Inhibition via Upregulated P2Y1 Purinoreceptors

To understand the pathogenesis of specific neuronal circuit dysfunction in Alzheimer’s disease (AD), we investigated the fate of three subclasses of “modulatory interneurons” in hippocampal CA1 using the App(NL-F/NL-F) knock-in mouse model of AD. Cholecystokinin- and somatostatin-expressing interneu...

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Detalles Bibliográficos
Autores principales: Shi, Anqi, Petrache, Alexandra L, Shi, Jiachen, Ali, Afia B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132926/
https://www.ncbi.nlm.nih.gov/pubmed/31407772
http://dx.doi.org/10.1093/cercor/bhz165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132926/
https://www.ncbi.nlm.nih.gov/pubmed/31407772
http://dx.doi.org/10.1093/cercor/bhz165

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