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NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension
BACKGROUND: NTP42 is a novel antagonist of the thromboxane prostanoid receptor (TP), currently in development for the treatment of pulmonary arterial hypertension (PAH). PAH is a devastating disease with multiple pathophysiological hallmarks including excessive pulmonary vasoconstriction, vascular r...
Autores principales: | Mulvaney, Eamon P., Reid, Helen M., Bialesova, Lucia, Bouchard, Annie, Salvail, Dany, Kinsella, B. Therese |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132963/ https://www.ncbi.nlm.nih.gov/pubmed/32252727 http://dx.doi.org/10.1186/s12890-020-1113-2 |
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