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The USP18 cysteine protease promotes HBV production independent of its protease activity

BACKGROUND: Hepatitis B virus (HBV) infection remains as one of the major public health problems in the world. Type I interferon (IFN) plays an essential role in antiviral defense by induced expression of a few hundred interferon stimulated genes (ISGs), including ubiquitin-specific protease 18 (USP...

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Detalles Bibliográficos
Autores principales: Li, Yujia, Yao, Min, Duan, Xiaoqiong, Ye, Haiyan, Li, Shilin, Chen, Limin, Yang, Chunhui, Chen, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133002/
https://www.ncbi.nlm.nih.gov/pubmed/32248821
http://dx.doi.org/10.1186/s12985-020-01304-2

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