Cargando…

TFPI2 suppresses breast cancer progression through inhibiting TWIST-integrin α5 pathway

BACKGROUND: Tissue factor pathway inhibitor 2 (TFPI2) participates in carcinogenesis of various tumors, and is associated with poor survival of breast cancer patients. However, the effect and underlying mechanism of TFPI2 on breast cancer progression remains to be investigated. METHODS: The expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Danyi, Qiao, Jingjing, He, Hongmei, Song, Jincheng, Zhao, Shanshan, Yu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133004/ https://www.ncbi.nlm.nih.gov/pubmed/32248791 http://dx.doi.org/10.1186/s10020-020-00158-2

Ejemplares similares

TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity
por: Stavik, Benedicte, et al.
Publicado: (2013)

Expression analysis of tissue factor pathway inhibitors TFPI-1 and TFPI-2 in Paralichthys olivaceus and antibacterial and anticancer activity of derived peptides
por: Wang, Guanghua, et al.
Publicado: (2021)

Factor V‐short and protein S as synergistic tissue factor pathway inhibitor (TFPIα) cofactors
por: Dahlbäck, Björn, et al.
Publicado: (2017)

Inhibition of tissue factor pathway inhibitor (TFPI) by ARC19499 improves clotting of hemophiliac blood
por: Gorczyca, Monika E, et al.
Publicado: (2010)

Inhibition of Tissue Factor Pathway Inhibitor (TFPI) as a Treatment for Haemophilia: Rationale with Focus on Concizumab
por: Chowdary, Pratima
Publicado: (2018)

TFPI2 Promotes Perivascular Migration in an Angiotropism Model of Melanoma
por: Mo, Jing, et al.
Publicado: (2021)

The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer
por: Hu, Haochang, et al.
Publicado: (2017)

Platelet full length TFPI-α in healthy volunteers is not affected by sex or hormonal use
por: Winckers, Kristien, et al.
Publicado: (2017)

Association study to evaluate TFPI gene in CAD in Han Chinese
por: Zhao, Ying, et al.
Publicado: (2017)

TFPI2 suppresses the interaction of TGF-β2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy
por: Guan, Guoying, et al.
Publicado: (2022)

MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2
por: Yan, Weiwei, et al.
Publicado: (2022)

Low expression of TFPI-2 associated with poor survival outcome in patients with breast cancer
por: Xu, Cheng, et al.
Publicado: (2013)

Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells
por: Andresen, Marianne S., et al.
Publicado: (2020)

Twist-mediated PAR1 induction is required for breast cancer progression and metastasis by inhibiting Hippo pathway
por: Wang, Yifan, et al.
Publicado: (2020)

A hydrophobic patch (PLVIVG; 1481–1486) in the B‐domain of factor V‐short is crucial for its synergistic TFPIα‐cofactor activity with protein S and for the formation of the FXa‐inhibitory complex comprising FV‐short, TFPIα, and protein S
por: Dahlbäck, Björn, et al.
Publicado: (2022)

Beneficial role of overexpression of TFPI-2 on tumour progression in human small cell lung cancer()
por: Lavergne, Marion, et al.
Publicado: (2013)

TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9
por: Wang, Guangli, et al.
Publicado: (2018)

miR-186 Suppresses the Progression of Cholangiocarcinoma Cells Through Inhibition of Twist1
por: Zhang, Ming, et al.
Publicado: (2019)

Regulation of factor V by the anticoagulant protease activated protein C: Influence of the B-domain and TFPIα
por: Ayombil, Francis, et al.
Publicado: (2022)

ZNF354C Mediated by DNMT1 Ameliorates Lung Ischemia-Reperfusion Oxidative Stress Injury by Reducing TFPI Promoter Methylation to Upregulate TFPI
por: Shi, Qi, et al.
Publicado: (2022)

MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium
por: Kremer, Veerle, et al.
Publicado: (2022)

Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells
por: Wang, Guangli, et al.
Publicado: (2017)

TFPI-2 Protects Against Gram-Negative Bacterial Infection
por: Ali, Mohamad N., et al.
Publicado: (2018)

Two ways of epigenetic silencing of TFPI2 in cervical cancer
por: Fullár, Alexandra, et al.
Publicado: (2020)

miR186 suppresses prostate cancer progression by targeting Twist1
por: Zhao, Xian, et al.
Publicado: (2016)

Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation
por: EL-Ashmawy, Nahla E., et al.
Publicado: (2021)

Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1α
por: Arnason, Terra, et al.
Publicado: (2015)

Regulation of factor V and factor V-short by TFPIα: Relationship between B-domain proteolysis and binding
por: Petrillo, Teodolinda, et al.
Publicado: (2021)

The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer
por: Lei, Ruixue, et al.
Publicado: (2022)

RNA interference targeting human integrin α6 suppresses the metastasis potential of hepatocellular carcinoma cells
por: Lv, Guannan, et al.
Publicado: (2013)

Sialidase NEU1 suppresses progression of human bladder cancer cells by inhibiting fibronectin-integrin α5β1 interaction and Akt signaling pathway
por: Zhou, Xiaoman, et al.
Publicado: (2020)

MDA-19 Suppresses Progression of Melanoma Via Inhibiting the PI3K/Akt Pathway
por: Dang, Ningning, et al.
Publicado: (2018)

TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response
por: Davies, Gerald F., et al.
Publicado: (2014)

Polyphyllin I suppresses the formation of vasculogenic mimicry via Twist1/VE-cadherin pathway
por: Xiao, Ting, et al.
Publicado: (2018)

TWIST2 and the PPAR signaling pathway are important in the progression of nonalcoholic steatohepatitis
por: Zhang, Yanmei, et al.
Publicado: (2021)

Long non-coding RNA AGAP2-AS1 exerts oncogenic properties in glioblastoma by epigenetically silencing TFPI2 through EZH2 and LSD1
por: Luo, Wenzheng, et al.
Publicado: (2019)

EZH2 inhibition suppresses endometrial cancer progression via miR-361/Twist axis
por: Ihira, Kei, et al.
Publicado: (2017)

CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways
por: Ke, Hengning, et al.
Publicado: (2012)

Genomic pathways modulated by Twist in breast cancer
por: Vesuna, Farhad, et al.
Publicado: (2017)

FoxO3a Inhibits Tamoxifen-Resistant Breast Cancer Progression by Inducing Integrin α5 Expression
por: Ricci, Elena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_95g44hc4a7a5mqbgcm2inq5bia