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Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture

INTRODUCTION: Life-threatening hemorrhage associated with low-energy pelvic fracture has been described in single cases in the literature. However, there is limited evidence available on the bleeding risk associated with hemodynamically stable osteoporotic pelvic fractures. The objective of this stu...

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Autores principales: Sng, Marcus, Gentle, Juliette, Asadollahi, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133069/
https://www.ncbi.nlm.nih.gov/pubmed/32284903
http://dx.doi.org/10.1177/2151459320911868
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author Sng, Marcus
Gentle, Juliette
Asadollahi, Saeed
author_facet Sng, Marcus
Gentle, Juliette
Asadollahi, Saeed
author_sort Sng, Marcus
collection PubMed
description INTRODUCTION: Life-threatening hemorrhage associated with low-energy pelvic fracture has been described in single cases in the literature. However, there is limited evidence available on the bleeding risk associated with hemodynamically stable osteoporotic pelvic fractures. The objective of this study was to estimate the bleeding risk associated with low-energy osteoporotic pelvic fractures in the elderly population. MATERIALS AND METHODS: A retrospective review of patients aged > 65 years old with pelvic fractures admitted between 2015 and 2018 was performed. Eighty-two patients were identified: 12 males and 70 females with a median age of 86 years. The median Charlson comorbidity index was 6 (interquartile range = 5-7). Eighty-one fractures were classified as lateral compression I or Tile A2, and 1 fracture was classified as lateral compression II or Tile B2. Forty patients were on concurrent anticoagulation treatment. In 4 patients on warfarin, this treatment was reversed on admission. RESULTS: The mean hemoglobin (Hb) level on arrival was 12.36 g/dL (±1.67 g/dL). There were significant drops in Hb levels on day 1 (Hb = 11.22 ± 1.86 g/dL, P < .001) and day 4 (Hb = 10.97 ± 1.6 g/dL, P < .001). Nine percent of patients required a blood transfusion. The mean baseline Hb level pre-transfusion was 8.33 g/dL (±1.15). Preexisting anticoagulation treatment did not predispose patients to greater decreases in Hb levels on day 1 (mean difference = 0.16 g/dL, P = .62) or day 4 (mean difference = 0.29 g/dL, P = .48) post-admission. DISCUSSION: An observed mean decrease in Hb level of up to 1.4 g/dL can occur in hemodynamically stable elderly patients with osteoporotic pelvic fractures, reflecting an approximate loss of 1.4 units of packed red blood cells. CONCLUSION: This degree of decrease in Hb may be clinically significant in geriatric patients with chronic anemia and a history of cardiovascular disease.
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spelling pubmed-71330692020-04-13 Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture Sng, Marcus Gentle, Juliette Asadollahi, Saeed Geriatr Orthop Surg Rehabil Original Article INTRODUCTION: Life-threatening hemorrhage associated with low-energy pelvic fracture has been described in single cases in the literature. However, there is limited evidence available on the bleeding risk associated with hemodynamically stable osteoporotic pelvic fractures. The objective of this study was to estimate the bleeding risk associated with low-energy osteoporotic pelvic fractures in the elderly population. MATERIALS AND METHODS: A retrospective review of patients aged > 65 years old with pelvic fractures admitted between 2015 and 2018 was performed. Eighty-two patients were identified: 12 males and 70 females with a median age of 86 years. The median Charlson comorbidity index was 6 (interquartile range = 5-7). Eighty-one fractures were classified as lateral compression I or Tile A2, and 1 fracture was classified as lateral compression II or Tile B2. Forty patients were on concurrent anticoagulation treatment. In 4 patients on warfarin, this treatment was reversed on admission. RESULTS: The mean hemoglobin (Hb) level on arrival was 12.36 g/dL (±1.67 g/dL). There were significant drops in Hb levels on day 1 (Hb = 11.22 ± 1.86 g/dL, P < .001) and day 4 (Hb = 10.97 ± 1.6 g/dL, P < .001). Nine percent of patients required a blood transfusion. The mean baseline Hb level pre-transfusion was 8.33 g/dL (±1.15). Preexisting anticoagulation treatment did not predispose patients to greater decreases in Hb levels on day 1 (mean difference = 0.16 g/dL, P = .62) or day 4 (mean difference = 0.29 g/dL, P = .48) post-admission. DISCUSSION: An observed mean decrease in Hb level of up to 1.4 g/dL can occur in hemodynamically stable elderly patients with osteoporotic pelvic fractures, reflecting an approximate loss of 1.4 units of packed red blood cells. CONCLUSION: This degree of decrease in Hb may be clinically significant in geriatric patients with chronic anemia and a history of cardiovascular disease. SAGE Publications 2020-04-02 /pmc/articles/PMC7133069/ /pubmed/32284903 http://dx.doi.org/10.1177/2151459320911868 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Sng, Marcus
Gentle, Juliette
Asadollahi, Saeed
Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title_full Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title_fullStr Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title_full_unstemmed Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title_short Bleeding Risk Associated With Hemodynamically Stable Low-Energy Pelvic Fracture
title_sort bleeding risk associated with hemodynamically stable low-energy pelvic fracture
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133069/
https://www.ncbi.nlm.nih.gov/pubmed/32284903
http://dx.doi.org/10.1177/2151459320911868
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