Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution

The Middle East respiratory syndrome coronavirus (MERS-CoV) was first described in 2012 and, subsequently, many cases were reported with a lower case fatality rate than initial cases. Humans can become infected within their communities and transmission can then be amplified in the healthcare setting...

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Detalles Bibliográficos
Autores principales: Al-Tawfiq, Jaffar A., Memish, Ziad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133228/
https://www.ncbi.nlm.nih.gov/pubmed/25178651
http://dx.doi.org/10.1016/j.tim.2014.08.001
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author Al-Tawfiq, Jaffar A.
Memish, Ziad A.
author_facet Al-Tawfiq, Jaffar A.
Memish, Ziad A.
author_sort Al-Tawfiq, Jaffar A.
collection PubMed
description The Middle East respiratory syndrome coronavirus (MERS-CoV) was first described in 2012 and, subsequently, many cases were reported with a lower case fatality rate than initial cases. Humans can become infected within their communities and transmission can then be amplified in the healthcare setting. Contact investigation among cases shows a variable amount of spread among family members and healthcare workers. So far, circulating virus strains remain similar under continuous monitoring, with no genetic changes. Here, we discuss the transmission pattern, phylogenetic evolution, and pathogenesis of MERS-CoV infection.
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spelling pubmed-71332282020-04-08 Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution Al-Tawfiq, Jaffar A. Memish, Ziad A. Trends Microbiol Article The Middle East respiratory syndrome coronavirus (MERS-CoV) was first described in 2012 and, subsequently, many cases were reported with a lower case fatality rate than initial cases. Humans can become infected within their communities and transmission can then be amplified in the healthcare setting. Contact investigation among cases shows a variable amount of spread among family members and healthcare workers. So far, circulating virus strains remain similar under continuous monitoring, with no genetic changes. Here, we discuss the transmission pattern, phylogenetic evolution, and pathogenesis of MERS-CoV infection. Elsevier Ltd. 2014-10 2014-08-29 /pmc/articles/PMC7133228/ /pubmed/25178651 http://dx.doi.org/10.1016/j.tim.2014.08.001 Text en Copyright © 2014 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Al-Tawfiq, Jaffar A.
Memish, Ziad A.
Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title_full Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title_fullStr Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title_full_unstemmed Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title_short Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution
title_sort middle east respiratory syndrome coronavirus: transmission and phylogenetic evolution
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133228/
https://www.ncbi.nlm.nih.gov/pubmed/25178651
http://dx.doi.org/10.1016/j.tim.2014.08.001
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