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Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave
Lactic acidosis is a recognized event in adult patients with acute severe asthma (ASA). Only a few cases have been reported in children. Hereinafter is reported the case of a 2-year-old girl hospitalized in the pediatric intensive care unit for ASA, which was treated with high-flow oxygen therapy an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133280/ https://www.ncbi.nlm.nih.gov/pubmed/25125034 http://dx.doi.org/10.1016/j.arcped.2014.06.024 |
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author | Perrin, C. Savy, N. Lang, M. Caron, N. Labbé, A. |
author_facet | Perrin, C. Savy, N. Lang, M. Caron, N. Labbé, A. |
author_sort | Perrin, C. |
collection | PubMed |
description | Lactic acidosis is a recognized event in adult patients with acute severe asthma (ASA). Only a few cases have been reported in children. Hereinafter is reported the case of a 2-year-old girl hospitalized in the pediatric intensive care unit for ASA, which was treated with high-flow oxygen therapy and intravenous methylprednisolone and salbutamol. During hospitalization, she had metabolic acidosis with a 7.29 pH, a 26 mmHg hypocapnia, and a decrease in bicarbonates to 12 mmol/L. The anion gap was increased to 20 mmol/L and lactates to 8 mmol/L. The work-up for a congenital metabolic disease was normal. Progression was propitious with spontaneous improvement of lactic acidosis, and the child was discharged from the intensive care unit after 72 h. The origin of lactic acidosis during ASA seems to be multifactorial. Although its recovery can be spontaneous, it is important to know how to identify it because it can worsen respiratory symptoms and can lead to incongruous therapeutic escalation. |
format | Online Article Text |
id | pubmed-7133280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71332802020-04-08 Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave Perrin, C. Savy, N. Lang, M. Caron, N. Labbé, A. Arch Pediatr Article Lactic acidosis is a recognized event in adult patients with acute severe asthma (ASA). Only a few cases have been reported in children. Hereinafter is reported the case of a 2-year-old girl hospitalized in the pediatric intensive care unit for ASA, which was treated with high-flow oxygen therapy and intravenous methylprednisolone and salbutamol. During hospitalization, she had metabolic acidosis with a 7.29 pH, a 26 mmHg hypocapnia, and a decrease in bicarbonates to 12 mmol/L. The anion gap was increased to 20 mmol/L and lactates to 8 mmol/L. The work-up for a congenital metabolic disease was normal. Progression was propitious with spontaneous improvement of lactic acidosis, and the child was discharged from the intensive care unit after 72 h. The origin of lactic acidosis during ASA seems to be multifactorial. Although its recovery can be spontaneous, it is important to know how to identify it because it can worsen respiratory symptoms and can lead to incongruous therapeutic escalation. Elsevier Masson SAS. 2014-10 2014-08-11 /pmc/articles/PMC7133280/ /pubmed/25125034 http://dx.doi.org/10.1016/j.arcped.2014.06.024 Text en Copyright © 2014 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Perrin, C. Savy, N. Lang, M. Caron, N. Labbé, A. Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title | Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title_full | Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title_fullStr | Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title_full_unstemmed | Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title_short | Acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
title_sort | acidose lactique chez un nourrisson au cours d’une crise d’asthme grave |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133280/ https://www.ncbi.nlm.nih.gov/pubmed/25125034 http://dx.doi.org/10.1016/j.arcped.2014.06.024 |
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