Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme

Rat antizyme gene expression requires programmed, ribosomal frameshifting. A novel autoregulatory mechanism enables modulation of frameshifting according to the cellular concentration of polyamines. Antizyme binds to, and destabilizes, ornithine decarboxylase, a key enzyme in polyamine synthesis. Ra...

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Detalles Bibliográficos
Autores principales: Matsufuji, Senya, Matsufuji, Tamiko, Miyazaki, Youichi, Murakami, Yasuko, Atkins, John F, Gesteland, Raymond F, Hayashi, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 1995
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133313/
https://www.ncbi.nlm.nih.gov/pubmed/7813017
http://dx.doi.org/10.1016/0092-8674(95)90450-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133313/
https://www.ncbi.nlm.nih.gov/pubmed/7813017
http://dx.doi.org/10.1016/0092-8674(95)90450-6

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