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Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme
Rat antizyme gene expression requires programmed, ribosomal frameshifting. A novel autoregulatory mechanism enables modulation of frameshifting according to the cellular concentration of polyamines. Antizyme binds to, and destabilizes, ornithine decarboxylase, a key enzyme in polyamine synthesis. Ra...
Autores principales: | Matsufuji, Senya, Matsufuji, Tamiko, Miyazaki, Youichi, Murakami, Yasuko, Atkins, John F, Gesteland, Raymond F, Hayashi, Shin-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133313/ https://www.ncbi.nlm.nih.gov/pubmed/7813017 http://dx.doi.org/10.1016/0092-8674(95)90450-6 |
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