The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue

The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfact...

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Detalles Bibliográficos
Autores principales: Kalicharran, Kishna, Dales, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1996
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133366/
https://www.ncbi.nlm.nih.gov/pubmed/8829334
http://dx.doi.org/10.1016/0966-842X(96)10045-7
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author Kalicharran, Kishna
Dales, Samuel
author_facet Kalicharran, Kishna
Dales, Samuel
author_sort Kalicharran, Kishna
collection PubMed
description The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfactory, hippocampal and cerebellar sites within the central nervous system, resulting in severe neuropathies.
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spelling pubmed-71333662020-04-08 The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue Kalicharran, Kishna Dales, Samuel Trends Microbiol Review The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfactory, hippocampal and cerebellar sites within the central nervous system, resulting in severe neuropathies. Published by Elsevier Ltd. 1996-07 1999-03-19 /pmc/articles/PMC7133366/ /pubmed/8829334 http://dx.doi.org/10.1016/0966-842X(96)10045-7 Text en Copyright © 1996 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Kalicharran, Kishna
Dales, Samuel
The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title_full The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title_fullStr The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title_full_unstemmed The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title_short The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
title_sort murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133366/
https://www.ncbi.nlm.nih.gov/pubmed/8829334
http://dx.doi.org/10.1016/0966-842X(96)10045-7
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