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Murine coronavirus infection: a paradigm for virus-induced demyelinating disease

A variety of neurological diseases in humans, including multiple sclerosis (MS), have been postulated to have a viral etiology. The use of animal models provides insights into potential mechanism(s) involved in the disease process. The murine coronavirus-induced demyelinating disease in rodents is o...

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Detalles Bibliográficos
Autores principales: Lane, Thomas E., Buchmeier, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133370/
https://www.ncbi.nlm.nih.gov/pubmed/9025229
http://dx.doi.org/10.1016/S0966-842X(97)81768-4
Descripción
Sumario:A variety of neurological diseases in humans, including multiple sclerosis (MS), have been postulated to have a viral etiology. The use of animal models provides insights into potential mechanism(s) involved in the disease process. The murine coronavirus-induced demyelinating disease in rodents is one such model for demyelinating disease in humans.