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Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report
The present study reports a rare case of a 65-year-old male patient with an exophytic ulcerative lesion in the gastric antrum. After performing a radical subtotal gastrectomy with D2 lymph node dissection and Billroth I gastrojejunostomy, histological analysis revealed a poorly differentiated adenoc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133413/ https://www.ncbi.nlm.nih.gov/pubmed/32216498 http://dx.doi.org/10.1177/0300060520904876 |
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author | Chen, Lei Yi, Xin Zou, Hong-Li Chen, Xu-An Gao, Shang Zhang, Pei-Hai |
author_facet | Chen, Lei Yi, Xin Zou, Hong-Li Chen, Xu-An Gao, Shang Zhang, Pei-Hai |
author_sort | Chen, Lei |
collection | PubMed |
description | The present study reports a rare case of a 65-year-old male patient with an exophytic ulcerative lesion in the gastric antrum. After performing a radical subtotal gastrectomy with D2 lymph node dissection and Billroth I gastrojejunostomy, histological analysis revealed a poorly differentiated adenocarcinoma combined with a biphasic pattern consisting of cytotrophoblasts and syncytiotrophoblasts. Immunohistochemical analysis showed a positive reaction with an anti-β-human chorionic gonadotropin antibody, and an abnormal increase in reproductive hormones. Furthermore, the patient succumbed to upper gastrointestinal hemorrhage in less than 3 months after the initial diagnosis, although the rupture of his liver metastasis was successfully treated by transhepatic artery embolization during the second admission. |
format | Online Article Text |
id | pubmed-7133413 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71334132020-04-13 Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report Chen, Lei Yi, Xin Zou, Hong-Li Chen, Xu-An Gao, Shang Zhang, Pei-Hai J Int Med Res Case Report The present study reports a rare case of a 65-year-old male patient with an exophytic ulcerative lesion in the gastric antrum. After performing a radical subtotal gastrectomy with D2 lymph node dissection and Billroth I gastrojejunostomy, histological analysis revealed a poorly differentiated adenocarcinoma combined with a biphasic pattern consisting of cytotrophoblasts and syncytiotrophoblasts. Immunohistochemical analysis showed a positive reaction with an anti-β-human chorionic gonadotropin antibody, and an abnormal increase in reproductive hormones. Furthermore, the patient succumbed to upper gastrointestinal hemorrhage in less than 3 months after the initial diagnosis, although the rupture of his liver metastasis was successfully treated by transhepatic artery embolization during the second admission. SAGE Publications 2020-03-27 /pmc/articles/PMC7133413/ /pubmed/32216498 http://dx.doi.org/10.1177/0300060520904876 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Chen, Lei Yi, Xin Zou, Hong-Li Chen, Xu-An Gao, Shang Zhang, Pei-Hai Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title | Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title_full | Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title_fullStr | Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title_full_unstemmed | Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title_short | Coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
title_sort | coexistence of gastric choriocarcinoma and adenocarcinoma with reproductive hormone secretion in a man: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133413/ https://www.ncbi.nlm.nih.gov/pubmed/32216498 http://dx.doi.org/10.1177/0300060520904876 |
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