Klotho Pathways, Myelination Disorders, Neurodegenerative Diseases, and Epigenetic Drugs

In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by acting on mitochondrial function, thereby her...

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Detalles Bibliográficos
Autores principales: Moos, Walter H., Faller, Douglas V., Glavas, Ioannis P., Harpp, David N., Kanara, Iphigenia, Mavrakis, Anastasios N., Pernokas, Julie, Pernokas, Mark, Pinkert, Carl A., Powers, Whitney R., Sampani, Konstantina, Steliou, Kosta, Vavvas, Demetrios G., Zamboni, Robert J., Kodukula, Krishna, Chen, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Comprehensive Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133426/
https://www.ncbi.nlm.nih.gov/pubmed/32257625
http://dx.doi.org/10.1089/biores.2020.0004

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