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Apelin-13 alleviated cardiac fibrosis via inhibiting the PI3K/Akt pathway to attenuate oxidative stress in rats with myocardial infarction-induced heart failure
The present study aimed to determine whether apelin-13 could attenuate cardiac fibrosis via inhibiting the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway to inhibit reactive oxygen species in heart failure (HF) rats. HF models were established by inducing ischemia myocardial infar...
Autores principales: | Zhong, Shan, Guo, Hongli, Wang, Hui, Xing, Dan, Lu, Tingting, Yang, Jing, Wang, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133518/ https://www.ncbi.nlm.nih.gov/pubmed/32207519 http://dx.doi.org/10.1042/BSR20200040 |
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