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Hepatocyte growth factor is upregulated in ischemic retina and contributes to retinal vascular leakage and neovascularization

In patients with macular edema due to ischemic retinopathy, aqueous levels of hepatocyte growth factor (HGF) correlate with edema severity. We tested whether HGF expression and activity in mice with oxygen‐induced ischemic retinopathy supports a role in macular edema. In ischemic retina, HGF was inc...

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Detalles Bibliográficos
Autores principales: Lorenc, Valeria E., Lima e Silva, Raquel, Hackett, Sean F., Fortmann, Seth D., Liu, Yuanyuan, Campochiaro, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133726/
https://www.ncbi.nlm.nih.gov/pubmed/32259049
http://dx.doi.org/10.1096/fba.2019-00074