BRAF V600E-mutated metastatic pediatric Wilms tumor with complete response to targeted RAF/MEK inhibition

Wilms tumor (WT) is the most common renal malignancy of childhood and accounts for 6% of all childhood malignancies. With current therapies, the 5-yr overall survival (OS) for children with unilateral favorable histology WT is greater than 85%. The prognosis is worse, however, for the roughly 15% of...

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Detalles Bibliográficos
Autores principales: Obasaju, Patience, Shahab, Shubin, Dunn, Emily, Rhee, Daniel S., Jiang, LiQun, Dome, Jeffrey S., Friedman, Alan D., Argani, Pedram, Pratilas, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133746/
https://www.ncbi.nlm.nih.gov/pubmed/32238401
http://dx.doi.org/10.1101/mcs.a004820

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