Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial

BACKGROUND: Uveitis associated with juvenile idiopathic arthritis is a cause of major ocular morbidity. A substantial proportion of children are refractory to systemic methotrexate and TNF inhibitors. Our aim was to study the safety and efficacy of tocilizumab in children with juvenile idiopathic ar...

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Detalles Bibliográficos
Autores principales: Ramanan, Athimalaipet V, Dick, Andrew D, Guly, Catherine, McKay, Andrew, Jones, Ashley P, Hardwick, Ben, Lee, Richard W J, Smyth, Matthew, Jaki, Thomas, Beresford, Michael W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134526/
https://www.ncbi.nlm.nih.gov/pubmed/32280950
http://dx.doi.org/10.1016/S2665-9913(20)30008-4

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