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Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China
OBJECTIVE: The aim of this study was to explore the prevalent characteristics of HBoV1 and its co-infection. METHODS: PCR was used to detect HBoV1-DNA (HBoV1) and other viruses. A multivariate logistic regression model was used to explore possibility of co-detected for related viruses. RESULTS: The...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134634/ https://www.ncbi.nlm.nih.gov/pubmed/25374017 http://dx.doi.org/10.3967/bes2014.110 |
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author | WU, Jian Jun JIN, Yu LIN, Na XIE, Zhi Ping YU, Jie Mei LI, Jin Song CAO, Chang Qing YUAN, Xin Hui SONG, Jin Rong ZHANG, Jing ZHAO, Yang GAO, Xiao Qian DUAN, Zhao Jun |
author_facet | WU, Jian Jun JIN, Yu LIN, Na XIE, Zhi Ping YU, Jie Mei LI, Jin Song CAO, Chang Qing YUAN, Xin Hui SONG, Jin Rong ZHANG, Jing ZHAO, Yang GAO, Xiao Qian DUAN, Zhao Jun |
author_sort | WU, Jian Jun |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to explore the prevalent characteristics of HBoV1 and its co-infection. METHODS: PCR was used to detect HBoV1-DNA (HBoV1) and other viruses. A multivariate logistic regression model was used to explore possibility of co-detected for related viruses. RESULTS: The positivity rates in Nanjing and Lanzhou were 9.38% (74/789) and 11.62% (161/1386), respectively (P<0.05). The HBoV1 positive group was younger than negative group (P<0.05). Seasonal differences were noted, with a higher frequency of infection in December and July. HBoV1-positive children [72.34% (169/235)] were co-infected with other respiratory viruses. Multifactorial analysis showed no correlations between HBoV1 and the clinical classification, region, gender, age, or treatment as an outpatient or in a hospital. Correlations were identified between HBoV1 infections with ADV (OR=1.53, 95% CI 1.03-2.28), RSV (OR=0.71, 95% CI 0.52-0.98), and IFVA (OR=1.77, 95% CI 1.00-3.13). CONCLUSIONS: Presence of HBoV1 in nasopharyngeal aspirates did not correlate with region or gender, although the prevalence of HBoV1 was higher in younger children. There were no correlations between HBoV1 and other variables, except for the season and ADV, RSV, or IFVA infections. |
format | Online Article Text |
id | pubmed-7134634 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71346342020-04-08 Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China WU, Jian Jun JIN, Yu LIN, Na XIE, Zhi Ping YU, Jie Mei LI, Jin Song CAO, Chang Qing YUAN, Xin Hui SONG, Jin Rong ZHANG, Jing ZHAO, Yang GAO, Xiao Qian DUAN, Zhao Jun Biomed Environ Sci Original Article OBJECTIVE: The aim of this study was to explore the prevalent characteristics of HBoV1 and its co-infection. METHODS: PCR was used to detect HBoV1-DNA (HBoV1) and other viruses. A multivariate logistic regression model was used to explore possibility of co-detected for related viruses. RESULTS: The positivity rates in Nanjing and Lanzhou were 9.38% (74/789) and 11.62% (161/1386), respectively (P<0.05). The HBoV1 positive group was younger than negative group (P<0.05). Seasonal differences were noted, with a higher frequency of infection in December and July. HBoV1-positive children [72.34% (169/235)] were co-infected with other respiratory viruses. Multifactorial analysis showed no correlations between HBoV1 and the clinical classification, region, gender, age, or treatment as an outpatient or in a hospital. Correlations were identified between HBoV1 infections with ADV (OR=1.53, 95% CI 1.03-2.28), RSV (OR=0.71, 95% CI 0.52-0.98), and IFVA (OR=1.77, 95% CI 1.00-3.13). CONCLUSIONS: Presence of HBoV1 in nasopharyngeal aspirates did not correlate with region or gender, although the prevalence of HBoV1 was higher in younger children. There were no correlations between HBoV1 and other variables, except for the season and ADV, RSV, or IFVA infections. The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd. 2014-11 2014-11-11 /pmc/articles/PMC7134634/ /pubmed/25374017 http://dx.doi.org/10.3967/bes2014.110 Text en © 2014 The Editorial Board of Biomedical and Environmental Sciences Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article WU, Jian Jun JIN, Yu LIN, Na XIE, Zhi Ping YU, Jie Mei LI, Jin Song CAO, Chang Qing YUAN, Xin Hui SONG, Jin Rong ZHANG, Jing ZHAO, Yang GAO, Xiao Qian DUAN, Zhao Jun Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title | Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title_full | Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title_fullStr | Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title_full_unstemmed | Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title_short | Detection of Human Bocavirus in Children with Acute Respiratory Tract Infections in Lanzhou and Nanjing, China |
title_sort | detection of human bocavirus in children with acute respiratory tract infections in lanzhou and nanjing, china |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134634/ https://www.ncbi.nlm.nih.gov/pubmed/25374017 http://dx.doi.org/10.3967/bes2014.110 |
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