Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015

The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 clos...

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Detalles Bibliográficos
Autores principales: WANG, Wen Ling, WANG, Hui Juan, DENG, Yao, SONG, Tie, LAN, Jia Ming, WU, Gui Zhen, KE, Chang Wen, TAN, Wen Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd. 2016
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135062/
https://www.ncbi.nlm.nih.gov/pubmed/27109133
http://dx.doi.org/10.3967/bes2016.027
Descripción
Sumario:The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.

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