Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015

The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 clos...

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Autores principales: WANG, Wen Ling, WANG, Hui Juan, DENG, Yao, SONG, Tie, LAN, Jia Ming, WU, Gui Zhen, KE, Chang Wen, TAN, Wen Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135062/
https://www.ncbi.nlm.nih.gov/pubmed/27109133
http://dx.doi.org/10.3967/bes2016.027
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author WANG, Wen Ling
WANG, Hui Juan
DENG, Yao
SONG, Tie
LAN, Jia Ming
WU, Gui Zhen
KE, Chang Wen
TAN, Wen Jie
author_facet WANG, Wen Ling
WANG, Hui Juan
DENG, Yao
SONG, Tie
LAN, Jia Ming
WU, Gui Zhen
KE, Chang Wen
TAN, Wen Jie
author_sort WANG, Wen Ling
collection PubMed
description The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China.
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spelling pubmed-71350622020-04-08 Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015 WANG, Wen Ling WANG, Hui Juan DENG, Yao SONG, Tie LAN, Jia Ming WU, Gui Zhen KE, Chang Wen TAN, Wen Jie Biomed Environ Sci Article The first imported Middle East respiratory syndrome (MERS) case in China was identified in May 2015. We determined the kinetics of antibody (IgG and IgM) and neutralizing antibodies against MERS-coronavirus (MERS-CoV) in this case before discharge. Moreover, no seroconversion was found among 53 close contacts by anti-MERS IgG antibody enzyme-linked immunosorbent assay (ELISA) of paired serum samples. These findings suggest that neither community nor nosocomial transmission of MERS-CoV occurred in China. The Editorial Board of Biomedical and Environmental Sciences. Published by Elsevier (Singapore) Pte Ltd. 2016-03 2016-04-25 /pmc/articles/PMC7135062/ /pubmed/27109133 http://dx.doi.org/10.3967/bes2016.027 Text en © 2016 The Editorial Board of Biomedical and Environmental Sciences Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
WANG, Wen Ling
WANG, Hui Juan
DENG, Yao
SONG, Tie
LAN, Jia Ming
WU, Gui Zhen
KE, Chang Wen
TAN, Wen Jie
Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title_full Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title_fullStr Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title_full_unstemmed Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title_short Serological Study of An Imported Case of Middle East Respiratory Syndrome and His Close Contacts in China, 2015
title_sort serological study of an imported case of middle east respiratory syndrome and his close contacts in china, 2015
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135062/
https://www.ncbi.nlm.nih.gov/pubmed/27109133
http://dx.doi.org/10.3967/bes2016.027
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