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Downregulation of endothelial nitric oxide synthase (eNOS) and endothelin-1 (ET-1) in a co-culture system with human stimulated X-linked CGD neutrophils

Phagocytes in patients with chronic granulomatous disease (CGD) do not generate reactive oxidative species (ROS), whereas nitric oxide (NO) production is increased in response to the calcium ionophore A23187 in CGD phagocytes compared with healthy phagocytes. Recently, patients with X-linked CGD (X-...

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Detalles Bibliográficos
Autores principales: Nakamura-Utsunomiya, Akari, Tsumura, Miyuki, Okada, Satoshi, Kawaguchi, Hiroshi, Kobayashi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135077/
https://www.ncbi.nlm.nih.gov/pubmed/32251485
http://dx.doi.org/10.1371/journal.pone.0230665