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Necessity of a more standardized virological characterization of rodents for aging studies
Characterization of the microbiological status is an important facet of a quality assurance program for laboratory animals. This paper addresses basic issues with regard to standardization of the characterization of murine viral status. Methods for such characterization include clinical signs, virus...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Published by Elsevier Inc.
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135186/ https://www.ncbi.nlm.nih.gov/pubmed/1791903 http://dx.doi.org/10.1016/0197-4580(91)90119-5 |
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author | van der Logt, Joseph T.M. |
author_facet | van der Logt, Joseph T.M. |
author_sort | van der Logt, Joseph T.M. |
collection | PubMed |
description | Characterization of the microbiological status is an important facet of a quality assurance program for laboratory animals. This paper addresses basic issues with regard to standardization of the characterization of murine viral status. Methods for such characterization include clinical signs, virus isolation, and serological tests. Significant considerations are screening profiles; sample collection, processing, and s shipment; and sampling schedules. International standardization of programs and methods to control and characterize the microbiological status of laboratory animals is being developed, and will be highly significant in future efforts to produce, control, and maintain laboratory animals free of viral infections. |
format | Online Article Text |
id | pubmed-7135186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1991 |
publisher | Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71351862020-04-08 Necessity of a more standardized virological characterization of rodents for aging studies van der Logt, Joseph T.M. Neurobiol Aging Article Characterization of the microbiological status is an important facet of a quality assurance program for laboratory animals. This paper addresses basic issues with regard to standardization of the characterization of murine viral status. Methods for such characterization include clinical signs, virus isolation, and serological tests. Significant considerations are screening profiles; sample collection, processing, and s shipment; and sampling schedules. International standardization of programs and methods to control and characterize the microbiological status of laboratory animals is being developed, and will be highly significant in future efforts to produce, control, and maintain laboratory animals free of viral infections. Published by Elsevier Inc. 1991 2003-03-25 /pmc/articles/PMC7135186/ /pubmed/1791903 http://dx.doi.org/10.1016/0197-4580(91)90119-5 Text en Copyright © 1991 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article van der Logt, Joseph T.M. Necessity of a more standardized virological characterization of rodents for aging studies |
title | Necessity of a more standardized virological characterization of rodents for aging studies |
title_full | Necessity of a more standardized virological characterization of rodents for aging studies |
title_fullStr | Necessity of a more standardized virological characterization of rodents for aging studies |
title_full_unstemmed | Necessity of a more standardized virological characterization of rodents for aging studies |
title_short | Necessity of a more standardized virological characterization of rodents for aging studies |
title_sort | necessity of a more standardized virological characterization of rodents for aging studies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135186/ https://www.ncbi.nlm.nih.gov/pubmed/1791903 http://dx.doi.org/10.1016/0197-4580(91)90119-5 |
work_keys_str_mv | AT vanderlogtjosephtm necessityofamorestandardizedvirologicalcharacterizationofrodentsforagingstudies |