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Autophagy compensates for defects in mitochondrial dynamics

Compromising mitochondrial fusion or fission disrupts cellular homeostasis; however, the underlying mechanism(s) are not fully understood. The loss of C. elegans fzo-1(MFN) results in mitochondrial fragmentation, decreased mitochondrial membrane potential and the induction of the mitochondrial unfol...

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Detalles Bibliográficos
Autores principales: Haeussler, Simon, Köhler, Fabian, Witting, Michael, Premm, Madeleine F., Rolland, Stéphane G., Fischer, Christian, Chauve, Laetitia, Casanueva, Olivia, Conradt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135339/
https://www.ncbi.nlm.nih.gov/pubmed/32191694
http://dx.doi.org/10.1371/journal.pgen.1008638