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A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada
Despite proactive measures to prevent raccoon rabies entering Canada from the United States, several incursions of this disease have occurred. The largest outbreak, first reported in December 2015 in the city of Hamilton, Ontario, has resulted in the reporting of 449 animal cases as of December 31,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135350/ https://www.ncbi.nlm.nih.gov/pubmed/32210439 http://dx.doi.org/10.1371/journal.pntd.0008113 |
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author | Nadin-Davis, Susan Buchanan, Tore Nituch, Larissa Fehlner-Gardiner, Christine |
author_facet | Nadin-Davis, Susan Buchanan, Tore Nituch, Larissa Fehlner-Gardiner, Christine |
author_sort | Nadin-Davis, Susan |
collection | PubMed |
description | Despite proactive measures to prevent raccoon rabies entering Canada from the United States, several incursions of this disease have occurred. The largest outbreak, first reported in December 2015 in the city of Hamilton, Ontario, has resulted in the reporting of 449 animal cases as of December 31, 2018. Initial phylogenetic studies on the index case suggested that this outbreak was not due to local cross-border spread from the Niagara region of the United States where raccoon rabies has persisted for several years. Phylogenetic analysis of whole genome sequences of a viral collection from the Hamilton area and several US states indicates that a long-distance translocation of a diseased animal from southeastern New York State was responsible for this incursion. The role of the skunk as a potential secondary host supporting persistence and / or spread of the virus is also examined. |
format | Online Article Text |
id | pubmed-7135350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-71353502020-04-09 A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada Nadin-Davis, Susan Buchanan, Tore Nituch, Larissa Fehlner-Gardiner, Christine PLoS Negl Trop Dis Research Article Despite proactive measures to prevent raccoon rabies entering Canada from the United States, several incursions of this disease have occurred. The largest outbreak, first reported in December 2015 in the city of Hamilton, Ontario, has resulted in the reporting of 449 animal cases as of December 31, 2018. Initial phylogenetic studies on the index case suggested that this outbreak was not due to local cross-border spread from the Niagara region of the United States where raccoon rabies has persisted for several years. Phylogenetic analysis of whole genome sequences of a viral collection from the Hamilton area and several US states indicates that a long-distance translocation of a diseased animal from southeastern New York State was responsible for this incursion. The role of the skunk as a potential secondary host supporting persistence and / or spread of the virus is also examined. Public Library of Science 2020-03-25 /pmc/articles/PMC7135350/ /pubmed/32210439 http://dx.doi.org/10.1371/journal.pntd.0008113 Text en © 2020 Nadin-Davis et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Nadin-Davis, Susan Buchanan, Tore Nituch, Larissa Fehlner-Gardiner, Christine A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title | A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title_full | A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title_fullStr | A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title_full_unstemmed | A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title_short | A long-distance translocation initiated an outbreak of raccoon rabies in Hamilton, Ontario, Canada |
title_sort | long-distance translocation initiated an outbreak of raccoon rabies in hamilton, ontario, canada |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135350/ https://www.ncbi.nlm.nih.gov/pubmed/32210439 http://dx.doi.org/10.1371/journal.pntd.0008113 |
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