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Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent

To study the effect of cell type-restricted hamster PrP expression on susceptibility to the hamster scrapie agent, we generated transgenic mice using a 1 kb hamster cDNA clone containing the 0.76 kb HPrP open reading frame under control of the neuron-specific enolase promoter. In these mice, express...

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Detalles Bibliográficos
Autores principales:	Race, Richard E., Priola, Suzette A., Bessen, Richard A., Ernst, Darwin, Dockter, Janel, Rall, Glenn F., Mucke, Lennart, Chesebro, Bruce, Oldstone, Michael B.A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 1995
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135899/ https://www.ncbi.nlm.nih.gov/pubmed/7576660 http://dx.doi.org/10.1016/0896-6273(95)90105-1

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