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A 6-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia

Recently, mRNA-expression signature enriched in LSCs was used to create a 17-gene leukemic stem cell (LSC17) score predictive of prognosis in adult AML. By fitting a Cox-LASSO regression model to the clinical outcome and gene-expression levels of LSC enriched genes in 163 pediatric participants of t...

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Detalles Bibliográficos
Autores principales:	Elsayed, Abdelrahman H., Rafiee, Roya, Cao, Xueyuan, Raimondi, Susana, Downing, James R., Ribeiro, Raul, Fan, Yiping, Gruber, Tanja A., Baker, Sharyn, Klco, Jeffery, Rubnitz, Jeffrey E., Pounds, Stanley, Lamba, Jatinder K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135934/ https://www.ncbi.nlm.nih.gov/pubmed/31645648 http://dx.doi.org/10.1038/s41375-019-0604-8

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