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RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations
Brain circuits comprise vast numbers of intricately interconnected neurons with diverse molecular, anatomical and physiological properties. To allow “user-defined” targeting of individual neurons for structural and functional studies, we created light-inducible site-specific DNA recombinases (SSRs)...
Autores principales: | Yao, Shenqin, Yuan, Peng, Ouellette, Ben, Zhou, Thomas, Mortrud, Marty, Balaram, Pooja, Chatterjee, Soumya, Wang, Yun, Daigle, Tanya L., Tasic, Bosiljka, Kuang, Xiuli, Gong, Hui, Luo, Qingming, Zeng, Shaoqun, Curtright, Andrew, Dhaka, Ajay, Kahan, Anat, Gradinaru, Viviana, Chrapkiewicz, Radosław, Schnitzer, Mark, Zeng, Hongkui, Cetin, Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135964/ https://www.ncbi.nlm.nih.gov/pubmed/32203389 http://dx.doi.org/10.1038/s41592-020-0774-3 |
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