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RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations

Brain circuits comprise vast numbers of intricately interconnected neurons with diverse molecular, anatomical and physiological properties. To allow “user-defined” targeting of individual neurons for structural and functional studies, we created light-inducible site-specific DNA recombinases (SSRs)...

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Detalles Bibliográficos
Autores principales: Yao, Shenqin, Yuan, Peng, Ouellette, Ben, Zhou, Thomas, Mortrud, Marty, Balaram, Pooja, Chatterjee, Soumya, Wang, Yun, Daigle, Tanya L., Tasic, Bosiljka, Kuang, Xiuli, Gong, Hui, Luo, Qingming, Zeng, Shaoqun, Curtright, Andrew, Dhaka, Ajay, Kahan, Anat, Gradinaru, Viviana, Chrapkiewicz, Radosław, Schnitzer, Mark, Zeng, Hongkui, Cetin, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135964/
https://www.ncbi.nlm.nih.gov/pubmed/32203389
http://dx.doi.org/10.1038/s41592-020-0774-3

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