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PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells

Animal cells use pattern-recognition receptors (PRRs) to detect specific pathogens. Pathogen detection mounts an appropriate immune response, including interferon and cytokine induction. The intracellular PRR-signaling pathways that detect DNA viruses have been characterized, particularly in myeloid...

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Detalles Bibliográficos
Autores principales:	Massa, Davide, Baran, Marcin, Bengoechea, Jose A., Bowie, Andrew G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135979/ https://www.ncbi.nlm.nih.gov/pubmed/32102850 http://dx.doi.org/10.1074/jbc.RA119.011400

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