Cargando…
Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply
Mitochondrial oxidative phosphorylation (OXPHOS) and cellular workload are tightly balanced by the key cellular regulator, calcium (Ca(2+)). Current models assume that cytosolic Ca(2+) regulates workload and that mitochondrial Ca(2+) uptake precedes activation of matrix dehydrogenases, thereby match...
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135991/ https://www.ncbi.nlm.nih.gov/pubmed/32094224 http://dx.doi.org/10.1074/jbc.RA119.011902 |