Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I

Heart muscle contractility and performance are controlled by posttranslational modifications of sarcomeric proteins. Although myosin regulatory light chain (RLC) phosphorylation has been studied extensively in vitro and in vivo, the precise role of cardiac myosin light chain kinase (cMLCK), the prim...

Descripción completa

Detalles Bibliográficos
Autores principales: Sevrieva, Ivanka R., Brandmeier, Birgit, Ponnam, Saraswathi, Gautel, Mathias, Irving, Malcolm, Campbell, Kenneth S., Sun, Yin-Biao, Kampourakis, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135997/
https://www.ncbi.nlm.nih.gov/pubmed/32086378
http://dx.doi.org/10.1074/jbc.RA119.011945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135997/
https://www.ncbi.nlm.nih.gov/pubmed/32086378
http://dx.doi.org/10.1074/jbc.RA119.011945

Ejemplares similares