Cargando…

Endogenous siRNAs promote proteostasis and longevity in germline-less Caenorhabditis elegans

How lifespan and the rate of aging are set is a key problem in biology. Small RNAs are conserved molecules that impact diverse biological processes through the control of gene expression. However, in contrast to miRNAs, the role of endo-siRNAs in aging remains unexplored. Here, by combining deep seq...

Descripción completa

Detalles Bibliográficos
Autores principales: Cohen-Berkman, Moran, Dudkevich, Reut, Ben-Hamo, Shani, Fishman, Alla, Salzberg, Yehuda, Waldman Ben-Asher, Hiba, Lamm, Ayelet T, Henis-Korenblit, Sivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136021/
https://www.ncbi.nlm.nih.gov/pubmed/32213289
http://dx.doi.org/10.7554/eLife.50896